As far as skinning goes, I found Uldum to be your best bet, by a good amount. Follow the red route down the river until you run out of crocadiles to skin, then head down to the cradle of the ancients. I find this route to be highly affective no matter how much time you're willing to devote to it. I spent two hours there and got around 200 savage leathers and 5 pristide hides. All of these sold withing two hours and I was 11k richer. Also, it's very important that you invest in an elixer of treasure finding when you're skinning. I got 2 stacks of Emberweave cloth and a few volatiles that added into that income.
Now as far as mining goes, I had a bit more trouble finding an amazing route to farm because I myself is not a miner. After doing some brief research this is the route that I found was the most effective. I included the herbalism route as well to save space. The black represents the best routes to farm, the grey is sub-optimal obsidium ore routes, the darker blue is the best whiptail route and the lighter blue is sub-optimal.
Hope you enjoy everybody, I will be posting again the next couple of days. Enjoy Cata and the most important rule of farming is NEVER GET BORED!!!